deskgameMahomes has passed for 260+ yards in each of his last three games. He has passed for 15 TDs in seven career starts against the Bills. Mahomes will get JuJu Smith-Schuster back from a hamstring injury this week to pair with new top WR DeAndre Hopkins.
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deskgameAgainst the Colts (4-6), things likely will be much closer. Indianapolis does its best work on the ground, and the Colts' defense has allowed the third-most yards rushing this season.
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deskgameNFL odds Week 13: Today’s betting lines include this week’s Eagles-Ravens point spread
