deskgameMahomes has passed for 260+ yards in each of his last three games. He has passed for 15 TDs in seven career starts against the Bills. Mahomes will get JuJu Smith-Schuster back from a hamstring injury this week to pair with new top WR DeAndre Hopkins.
deskgameThe Wolverines will be missing their top three rushers and their top two pass catchers. The top running back on the depth chart will be Benjamin Hall, who had 44 yards on 13 carries this season. The top two pass catches will be WR Semaj Morgan and TE Marlin Klein, who combined for 35 receptions, 235 receiving yards and one touchdown this season.
deskgameThe offenses are mainly intact. However, Michigan will miss RB Donovan Edwards. That will affect how Michigan runs an offense that averaged an underwhelming 22 points per game.
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