deskgameKickoff is scheduled for 4:30 p.m. EST on Saturday at M&T Bank Stadium.
deskgameMahomes has passed for 260+ yards in each of his last three games. He has passed for 15 TDs in seven career starts against the Bills. Mahomes will get JuJu Smith-Schuster back from a hamstring injury this week to pair with new top WR DeAndre Hopkins.
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