deskgameMahomes has passed for 260+ yards in each of his last three games. He has passed for 15 TDs in seven career starts against the Bills. Mahomes will get JuJu Smith-Schuster back from a hamstring injury this week to pair with new top WR DeAndre Hopkins.
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deskgameInstead, Syracuse QB Kyle McCord went off for 380 yards and three touchdowns, as Miami blew a 21-0 lead. Iowa State QB Rocco Becht ranks 15th nationally in passing yards with 22 touchdowns and nine interceptions. Watch for the Hurricanes to cover the spread, while the Cyclones provide enough scoring to reach the over.
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